FIASCO (Fragment-based Interactive Assembly for protein Structure prediction with COnstraints) is a C++ constraint solver optimized to address studies related to the analysis and prediction of the three-dimensional structure of proteins.
Its conceptual declarative nature allows an easy manipulation of constraints targeted at describing protein sequence and structural properties, interaction forces fields, spatial local and global constraints, etc.
Theoretical and Practical info about FIASCO can be retrieved following the tags above (Main Publications, Software, Extra Material, etc.)
What can FIASCO do? Some application examples.
- Protein 3D structure prediction
- Protein loops modeling
- Reconstruction of protein parts (sub-structures)
- Analysis of proteins flexibility
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